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By Joshua Mitteldorf

Because the Nineteen Nineties, laboratory characterization of getting older has been diverging from predictions of evolutionary conception, particularly within the sector of genetics. at the same time, a technology of multilevel choice has came upon its position within the evolutionary literature. the writer means that facts warrants attention of a brand new paradigm for evolution of getting older, and proposes the demographic thought of senescence, wherein getting older has Read more...

summary: because the Nineties, laboratory characterization of getting older has been diverging from predictions of evolutionary concept, in particular within the sector of genetics. at the same time, a technology of multilevel choice has discovered its position within the evolutionary literature. the writer means that facts warrants attention of a brand new paradigm for evolution of getting older, and proposes the demographic concept of senescence, wherein getting older has been affirmatively chosen since it degrees the demise expense through the years, assisting to stabilize inhabitants dynamics and forestall extinctions

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Extra resources for Aging is a group-selected adaptation: theory, evidence, and medical implications

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In the second, control of the CR response was traced to the transcription factor skn-1 acting in two neurons in * The best known of these genes is called daf16 in the worm and its homolog in mammals is called foxoA3. ) Hormesis 11 the brain. This is a clear example of a “deliberate” adaptation to shorten the length of life for the sake of population regulation, and it is not arranged automatically through chemical signals, but actually “calculated” by the nerve cells, based on sensory input. Caloric Restriction and Population Regulation The Caloric Restriction adaptation is very general across the animal kingdom.

This is true even though both Sanicula and humans are mortal and have similar lifespans. All will eventually die and in fact the average human may live longer than the average Sanicula shrub; but the last human of our generation will be long gone while Sanicula that came into the world at the same time are still hanging on. Semelparity Equals Sudden Death A semelparous plant or animal is defined by the fact that it reproduces just once in a lifetime; but as it happens, almost all semelparous animals and plants die promptly after reproduction.

298(5594): p. 830-4. 57. Hsin, H. and C. Kenyon, Signals from the reproductive system regulate the life span of C. elegans. Nature, 1999. 399(6734): p. 362-366. 58. , The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake. J. , 1986. 116(4): p. 641-54. 59. , Dietary modulation of reproductive function, In: Modulation of Aging Processes by Dietary Restriction, B. Yu, Editor. 1994, CRC Press: Cleveland, OH. p. 221-246. 60. , Effects of exercise and dietary restriction on energy metabolism and longevity, In: Modulation of Aging Processes by Dietary Restriction, B.

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