Download Aging Research - Methodological Issues by Carmen García-Peña, Luis Miguel Gutiérrez-Robledo, Mario PDF

By Carmen García-Peña, Luis Miguel Gutiérrez-Robledo, Mario Ulises Pérez-Zepeda

This e-book stories classical epidemiological and scientific learn reviews, with a spotlight on getting older. Chapters disguise methodological subject matters just like the medical procedure, ethics, and the results of sure exclusion standards and the paintings contains a examine scientific ideas like multi morbidity, frailty and performance. The authors exhibit the problems and demanding situations for researchers of age and getting older, and in addition think about the interpretation of clinical wisdom, from uncomplicated to scientific and from medical to public regulations of social and wellbeing and fitness care.

The specialize in getting older is what provides this booklet its useful viewpoint on study technique. All authors have massive event in getting older, geriatrics or gerontology and every bankruptcy comprises either a theoretical framework and functional examples of reports in getting older. Readers will realize research designs which are reviewed for uncomplicated constitution, major flaws and merits and are analyzed for particular stipulations and variables concerning aging.

This textual content is fitted to either future health care pros taking care of older adults and researchers who're new to investigate in getting older. it really is proper around the disciplines, together with medication, psychology, social sciences and dentistry and it helps studying with graphs and figures.

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On the other hand, the fruit fly, Drosophila melanogaster, which has a short life expectancy, low cost and easy maintenance, has allowed the identification of several genes of TOR signaling pathway in regulating longevity [36, 37]. D. melanogaster allows continuous study of aging and avoids the influence of newly divided cells because their cells are post-mitotic (except for some cells of the gut and gonads). Its longevity is altered by various environmental manipulations such as, temperature, reproductive status and dietary food or drug content [37].

Unlike prevalence studies, case studies may have a follow-up on the subject to learn the nature of the illness described; this aspect is shared in the case series design. In the example chosen to illustrate a case study from the set of older adults, a case is described of systemic lupus erythematosus accompanied by primary biliary cirrhosis [7]. The illness in other age groups is not common, and much less so in older adults, so that in the description of the particular characteristics found, new knowledge from the case may be learned.

The immunology profile confirmed: positivity in the antinuclear antibodies (ANA) with titer 1:400 and anti-dsDNA 115 IU / ml, with serum complement normal. The following antibodies were negative: anti-La, anticardiolipin, lupus anticoagulant, anti-SM, anti-RNP, anti-SCL-70, anticentromere, rheumatoid factor, and anti-citrullinated peptide.

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